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pentobarbital will minimize the level or impact of aripiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will decrease the extent or influence of conivaptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

Keep an eye on Closely (1)pentobarbital will lower the extent or outcome of levamlodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will decrease the extent or influence of nateglinide by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Check.

CYP3A4 inducers could raise the formation in the neurotoxic/nephrotoxic ifosfamide metabolite, chloroacetaldehyde. Carefully keep an eye on sufferers getting ifosfamide with CYP3A4 inducers for toxicities and think about dose adjustment.

pentobarbital will minimize the extent or influence of larotrectinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

Possibly improves toxicity of the other by pharmacodynamic synergism. Prevent or Use Alternate Drug. Profound sedation, respiratory depression, coma, and Demise may perhaps outcome if coadministered. Reserve concomitant prescribing of here these drugs in people for whom other treatment method selections are inadequate. Restrict dosages and durations on the minimum essential. Keep track of carefully for indications of respiratory depression and sedation.

pentobarbital will lessen the extent or outcome of methylprednisolone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

pentobarbital will reduce the extent or impact of budesonide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will minimize the extent or outcome of etoposide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will minimize the extent or influence of tamoxifen by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

If not able to prevent, double recent pralsetinib dose beginning on Working day 7 of coadministration with sturdy CYP3A inducer. After inducer continues to be discontinued for at least 14 days, resume prior pralsetinib dose.

With therapeutic doses of TCAs, barbiturates boost metabolism and decrease blood concentrations of TCAs.

pentobarbital will lessen the level or outcome of alosetron by influencing hepatic enzyme CYP2C9/10 metabolism. Minimal/Importance Unidentified.